Tretinoin cream

Tretinoin Cream is a topical medication formulated with the active ingredient tretinoin, a derivative of vitamin A. This cream is specifically designed to address various skin concerns, including acne, fine lines, wrinkles, and skin discoloration. By promoting the turnover of skin cells,it  helps to unclog pores, reduce inflammation, and improve the overall texture and appearance of the skin.

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What is Tretinoin Cream 0.025%? 

Tretinoin is made from both retinoids and vitamin A. It’s best to put it on at night because that lowers the chance that the sun will damage your skin. Tretinoin may cause some initial redness, itching, or burning in some patients. These reactions, if any, usually subside within three weeks as the skin gets used to the medication.

What Does Tretinoin Do Exactly?

Even though the exact way that Tretinoin works isn’t known, there is proof that topical Tretinoin makes follicular epithelial cells stick together less. Additionally, Tretinoin stimulates mitotic activity and increases follicular epithelial cell turnover, causing the comedones’ extrusion.

The benefit of Tretinoin 0.05 Cream

Skincare Use
Most of the time, Tretinoin treats both inflammatory and non-inflammatory acne. Using topical retinoids to treat acne vulgaris is supported by several trials.

Leukemia Use
PML-RARα, the gene responsible for certain types of leukaemia, can be forced into remission by Tretinoin. It is a product of the t(15;17) translocation which gives rise to the PML::RARα fusion gene.
Tretinoin has been studied in clinical trials, and it has been found that:
>It improves response rates to chemotherapy in people with acute promyelocytic leukaemia (APL)
>It improves remission duration in APL patients who have had an initial relapse
>It dramatically reduces relapse rate during maintenance therapy for APL

Photoaging treatment
The Food and Drug Administration (FDA) of the United States has given their blessing to using the prescription medicine tretinoin to treat the outward manifestations of ageing. Tretinoin has been shown to improve the look of fine lines, wrinkles, elastosis, and skin roughness resulting from photoaging in people over age 25. Evidence suggests that Tretinoin works best when used daily for several months; improvements can last up to 1 year after therapy is stopped.
+ Gentleness
+ Ease of use: lotion with normal penetration
+ Large range of tolerable dose: 0.05%~0.1% tretinoin/g cream
+ Effect: wrinkle reduction and improved skin texture [1]
+ Multiple clinical studies conducted in Asia, Europe, and America; Korea university medical centre reported 76.7% effectiveness after 8 weeks and 88.5% excellence after 18 weeks; the Japan pharmaceutical association reported 71% effectiveness after 6‐10 weeks. (reviews on http://www.ncbi.nlm.nih.gov/pubmed/16131943, http://www.ncbi.nlm.nih

How to Use ?

Applying more medication than recommended will not improve your results but may increase side effects.
This medication is for use on the skin only. Do not use it on irritated or broken skin.
Clean the affected area before applying this medication. Use your usual soap and warm water.
Keeping this drug away from your eyes, nose, and mouth is essential.
This medication is usually applied twice a day. It is best to apply it in the morning because it may cause some skin redness, peeling, or dryness and increase sensitivity to sunlight.
Do not cover the treated area with bandages or dressings unless otherwise directed by your doctor.
To get the most benefit from this product, use it regularly for 2 weeks to 1 month, depending on the area of your face affected by rosacea. The medication should be applied once each day at bedtime. Rosacea may occur more frequently during the initial stages of treatment but generally will be controlled after about 12 weeks of continued therapy.
If you experience a severe reaction to the drug, you should immediately stop using it, contact your doctor, or go to the nearest emergency room.

Side Effect of Tretinoin

Skin redness, dryness, itching, scaling, or burning sensations where the medication is applied.
Mild skin peeling during the first few weeks of treatment.
Changes in skin colour.
These side effects usually clear up after continued use. Tell your doctor if any of them persist or worsen.
Note:- For more Side Effects, Please Consult your Doctor

Dosage for Acne Treatment

Dosage for general health (not for acne treatment): Adults and teenagers—1 to 5 grams daily. Children—Use as directed by your doctor.
Use only directed.
Do not apply to your chest, back, or irritated skin areas.
Avoid over-applicating this medication by using only enough to cover the affected area.


Use caution if you have hypersensitivity to the active ingredient or vitamin A-related drugs (such as Tretinoin and isotretinoin).
Avoid contact with eyes, ears, and mouth.
Do not use this product if pregnant or breastfeeding.
Use caution if you have allergies to other topical treatments applied to the face.
Tell your doctor right away if any of these effects occur. You should avoid prolonged sun exposure, sunlight, and artificial UV rays (such as tanning beds or UVA/UVB treatment) while using this medication because it may increase your sensitivity to sunlight and induce sunburn.


Keep the gel in a cool, dry place.
Don’t freeze it or put it in too much heat or light.
Keep away from children.

Is Tretinoin and Retinol Are Same

Tretinoin, a form of retinoic acid, works immediately on your skin. In contrast, retinol can only become retinoic acid once it has been applied to the skin and undergone a conversion.
You should know Both skin ageing treatments; let’s compare them in 6 key points.
Tretinoin is a retinoic acid that pulls moisture out of the skin by causing cell shrinkage; meanwhile, retinol converts itself to a retinoic acid called all-trans-retinoic acid at the dermal surface.
Tretinoin can give you severe skin irritation, while retinol is less irritating than Tretinoin due to its conversion to retinoic acid. However, when misused, both can give you redness, dryness, and peeling.
. Tretinoin is about 4~5 times stronger as compared to retinol. If used improperly, Tretinoin might cause darkening or skin damage. To minimize this risk, always ensure your skin is spotless and makeup-free when using topical Tretinoin at higher concentrations (1% or more) or over a large skin area (like the whole face). Always use sunscreen when using topical Tretinoin.
On the other hand, Tretinoin can only be obtained through a valid physician’s prescription (for the treatment of acne, for example). In contrast, retinol can be bought without a prescription and over the counter.
While both are used for anti-ageing, tretinoin cream is the best choice to reduce fine lines and wrinkles, but it is more likely to irritate your skin.
Retinol takes longer to show results on your skin, while Tretinoin works more quickly—usually in one to two weeks.

FAQ For Tretinoin Cream

Tretinoin cream can be irritating, especially for individuals with sensitive skin. It is crucial to start with a lower concentration and slowly raise it as your body can handle it. If you have a lot of swelling, talk to your doctor about what to do. Dryness or irritation. They may recommend adjusting the frequency of application or switching to a mild formulation.

The effects of Tretinoin cream may vary from person to person. Generally, it may take several weeks to notice an improvement in acne and several months to see a reduction in fine lines and wrinkles. Consistent use of the medication is critical to achieving optimal results.

It is generally safe to use Tretinoin cream with other skincare products, but it’s important to avoid using products that can be irritating or drying. Harsh cleansers, exfoliants, and products containing alcohol may exacerbate the side effects of Tretinoin cream. It’s always a good idea to consult your healthcare provider or dermatologist for personalized advice on your skincare routine.

Tretinoin cream is not recommended for use during pregnancy or while breastfeeding. It is a category C drug for use during pregnancy, which means there may be risks to the unborn child.


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